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I-SMAD PROTEINS
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DeCS
Descriptor
English
:
Smad Proteins, Inhibitory
Descriptor
Spanish
:
Proteínas Smad Inhibidoras
Descriptor
Portuguese
:
Proteínas Smad Inibidoras
Synonyms
English
:
I-Smad Proteins
Inhibitory Smad Proteins
Tree Number:
D12.644.360.024.334.200
D12.776.157.057.170.249
D12.776.476.024.428.249
Definition
English
:
A sub-family of
smad proteins
that inhibit cell signaling by RECEPTOR-REGULATED
SMAD PROTEINS
. They form autoinhibitory
feedback
loops in the TGF-BETA signaling pathway and mediate signaling cross-talk with other signaling pathways
History Note
English
:
2006
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
50785
Unique Identifier:
D051897
Occurrence in VHL
:
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CID-10
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